“Explosive” cell death gene variant carried by millions of people

Researchers have found that millions worldwide carry a gene variant that controls ‘explosive’ cell death and is linked to inflammation. They say it may explain why some people are prone to developing inflammatory diseases.

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A cup in the mouth may replace a needle in the arm for drug delivery

Nobody likes getting needles, but unfortunately there are some medications that can only be administered via injection. That could be about to change, however, thanks to the invention of a suction cup that you stick in your mouth.

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Call to revise hand arthritis treatments due to efficacy concerns

Researchers have called for a review of the recommendations for the treatment of hand arthritis, after a large study revealed that injections were as ineffective as a placebo for pain relief. Injections are considered the most effective pain reliever.

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Vagus nerve important for heart function during exercise, not just rest

A new study has found that during exercise, the vagus nerve, essential to the body’s ‘rest and digest’ response, has a more important role in heart function than we thought. The findings could help treat diseases like heart failure.

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Genetic mechanism linking zinc to diabetes & liver disease uncovered

Researchers have identified the mechanism underlying the protective role zinc has in type 2 diabetes and the fatty liver disease associated with the condition. The findings open the door to developing a novel diabetes treatment.

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Light therapy helps the brain clear out toxic Alzheimer’s proteins

A new study has found that light therapy applied to mice during deep sleep increased the brain’s ability to clear away beta-amyloid protein, which may lead to a drug-free, non-invasive way treatment for Alzheimer's disease.

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Coffee compound improves age-related decline in memory and learning

A new study has found that a bioactive compound found in coffee beans improved learning and memory decline in aged mice. The findings open the door to developing a supplementary medicinal compound to treat or prevent age-related cognitive decline.

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Targeted gene therapy helps completely paralyzed mice walk again

A complete spinal cord injury results, tragically, in total paralysis of all limbs and muscles below the injury site. But now, scientists at EPFL have demonstrated in mice a new gene therapy that can regenerate nerves and restore the ability to walk.

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New gene-editing tool reduces unintended mutations by more than 70%

Splitting the gene editor used in traditional CRISPR technology creates a more precise tool with significantly less chance of causing unintended mutations, a new study has found. The novel tool could correct half of the mutations that cause disease.

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Common sweetener now linked to impaired memory and learning

Two months on from it being declared safe by the FDA, aspartame is again making headlines for the wrong reasons, this time for its potential negative impact on learning and memory. In a mice study, these cognitive impairments were passed on to young.

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