Vertex and CRISPR Therapeutics presented new data from one of the first trials testing gene-editing therapy in human subjects. Fifteen months on from first patient treatment, the therapy is showing remarkable efficacy treating two rare blood diseases.

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Researchers have succeeded in activating a hibernation-like state in mice and rats, opening up the possibility that this type of “suspended animation” might eventually be used for preserving human organs for transplant, or even deep space travel.

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When it comes to monitoring electrical activity in the brain, patients typically have to lie inside a large magnetoencephalography (MEG) machine. That could soon change, as scientists have developed a new version of a helmet that does the same job.

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Scientists have been exploring the connection between poor sleep and early death and found a type of molecule that appears to play a facilitating role, raising the prospect of new treatments and furthering our understanding of the mysteries of sleep.

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Scientists have discovered a new mechanism to help illustrate the rapid antidepressant qualities of ketamine. Imaging patients with depression revealed ketamine’s effects are a result of its interaction with a particular kind of serotonin receptor.

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Imagine a device that lets people with diabetes use an app to give themselves a boost of insulin when they need it, without an injection. A prototype device can do just that, using electricity to control gene expression in encapsulated beta cells.

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In organ transplants, rejection by the recipient's immune system is a risk. Now researchers at Yale have discovered a molecule that plays a role in triggering a slow-acting type of rejection, which could be blocked to give patients a better outlook.

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In 2017, scientists found the first direct evidence that autoimmunity may play a role in the onset of Parkinson’s disease, and have now uncovered further evidence of how the immune system contributes to the development of the disease.

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Through advanced imaging, scientists have identified the binding sites that certain molecules use to interact with brakes for cancer, revealing how drugs could be used to activate this “off-switch” and keep the disease in check.

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Although no one likes getting blood samples drawn or having their skin pricked, these are the most common methods of testing for allergies. Thanks to a new study, however, such uncomfortable pokes could soon be replaced with painless nasal swabs.

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